Ingqwalaselo ye-SNRI yePanic Disorder
Ngokuqhelekileyo kunqunywe ukunyangwa kwemizwa kunye nokukhathazeka, i-serotonin kunye ne-norepinephrine reuptake inhibitors enye yeyona ndlela yonyango eqhelekileyo yokukhathazeka kwesifo .
Yintoni i-Serotonin kunye ne-Norepinephrine Reuptake Inhibitors?
I-Serotonin kunye ne-norepinephrine reuptake inhibitors, ezincishiswe kwi-SNRIs, ziyodwa kwiklasi yeemithi ezichasayo. Ezinye zeendlela eziqhelekileyo ze-SNRI ziquka i- Effexor (venlafaxine), i-Cymbalta ( duloxetine ) kunye ne-Pristiq ( desvenlafaxine ).
Ezi ngxaki zokuxhatshazwa zivame ukunyangwa ukunyanga izifo zengqondo, ezifana nokugula okukhulu nokuphazamiseka kwengqondo .
I-SNRIs sele ifunyenwe ngokukhuseleka kwaye iphumelele ngokuphatha iingxaki zokuxhalabisa, kuquka ukuphazamiseka kwesifo , ukuphazamiseka okunyanzelekileyo ( OCD ), ingxaki yokukhathazeka kwentlalo, ingxaki yokukhathazeka jikelele ( GAD ), kunye ne-posttraumatic disorder disorder ( PTSD ). Ukongezelela, ii-SSNRI zinokuphucula ngokuphumelelayo intlungu eqhubekayo ebangelwa zizimo ezithile, ezifana ne-fibromyalgia kunye nesifo esingapheliyo.
Ba sebenza Njani?
Ingqondo yomntu iqulethe amakhulu amakhulu eendwendwe zamakhemikhali ezibizwa nge-neurotransmitters. Ezi zithunywa zijongene nokuqondisa ulwazi kulo lonke ubuchopho. Kukholelwa ukuba ukuba enye okanye ngaphezulu kwala ma-neurotransmitter ayinakulinganisela, inokubangela ukuba umntu ahlakulele ingqondo okanye ingxaki yokuxhalabisa.
I-serotonin neurotransmitters kunye ne- norepinephrin zicingelwa ukuba zixhomekeke ngakumbi kwi-disorder disorder.
Bobabini i-neurotransmitters badlala indima ekulawuleni imisebenzi ethile kunye neemvakalelo ezinokuchaphazela ukuqala kwesi siko. I-Serotonin idibaniswe nokulawulwa kwemizwa kunye nokulala. I-Norepinephrine inoxanduva lokuba umntu uphendule njani uxinzelelo kunye nokuxhalabisa kwaye ihambelana nempendulo yokulwa okanye ye-flight .
I-SNRIs isebenze ekuchaphazeni zombini i-serotonin kunye ne-norepinephrin ngokuthintela ukuba iisilini zomntu zisuke zikhupha ngokukhawuleza la ma-neurotransmitters. Ngokuzinzisa aba baxhasi be-neurotransmitters, ii-SNRI zinokukunceda ukuphucula imvakalelo yomntu, ukunciphisa iimvakalelo zokuxhalabisa, kunye nokunciphisa ukuhlaselwa kwexhala . I-SNRI maxa wambi idideka kunye ne-serotonin reuptake inhibitors ( SSRIs ) ekhethiweyo , ezifana nezidandlululo, kodwa kuphela umsebenzi ochaphazela i-serotonin.
Ngaba kukho naziphi na iimpembelelo zangasese zokusebenzisa i-SNRIs?
Kunokwenzeka ukuba ube nemiphumo emibi echaphazelekayo xa uthatha i-SNRIs. Ezinye zeziphumo eziqhelekileyo ezichaphazelekayo ze-SNRI ziquka:
- Isihlunu okanye ukuhlanza
- Umlomo omile
- Ukulala nokukhathala
- Intloko
- Iziphumo zecala lezesondo
- Ukwandisa ukwesaba
- Ubuhlungu besisu okanye isisu esiswini
- Izifo zokulala
Ezi ziphumo zecala kufuneka ziphele ngokukhawuleza ixesha. Buza udokotela wakho ukuba iziphumo ezingasayi kuphucula okanye zimbi. Kunokwenzeka ukuba ufumane uncedo olunzulu lweziyobisi ezivela kwi-SNRIs. Qhagamshelana nekhemisi okanye ugqirha ngokukhawuleza ukuba ufumana iimpawu zokuxhatshazwa kwezidakamizwa, ezifana nokuvuvukala emlonyeni, ubuso, okanye ulwimi, ukukwazi ukuphefumula, ukukhawuleza, ukukhawuleza, kunye nemihlathi.
Ngaba kukho naziphi na izicalulo zokuthatha i-SNRIs?
Isibhengezo seBhokisi eliMnyama: Ngo-2007, i-United States Yokutya kunye nezoLawulo lweeDrug (i-FDA) yanikezela isiluleko esaziwa njengesilumkiso sebhokisi emnyama.
Ngeli lumkiso, i-FDA iqaphele ukuba ukusebenzisa i-SNRIs kunye neminye imishanguzo yokuxhatshazwayo kunokukhokelela kwiingcamango nezenzo zokuzibulala. Unonophelo olongezelelweyo kunye nokubeka iliso kufuneka kuthathelwe kubantwana, abaselula kunye nabaselula abasithatha la mayeza, njengoko basengozini enkulu yokufumana ezi ziphumo ezimbi.
Ukusebenzisana kwezidakamizwa: Ezinye iyeza kufuneka zingathathwa kunye ne-SNRIs. Gcina ugqirha wakho ngokukhawuleza kunye nanoma yimaphi amayeza anqunyiwe kunye naphezu kwe-counter.
Ukusetyenziswa kotywala : Ukusela utywala kunokuphakamisa inetyhefu ye-SNRIs, enokuchaphazela ukuphumelela kwezi zonyango ezichasayo.
IiNdawo eziZodwa:
Ukukhulelwa / Ukongika - I-SNRI inokudluliselwa ukusuka kumama ukuya kumntwana ngexesha lokukhulelwa okanye ngexesha loongikazi. Ukuba ukhulelwe okanye unonesi, xubusha ingozi ebalulekileyo yokuthatha i-SNRIs kunye nogqirha wakho.
Abadala abadala - abaninzi abantu abadala kakhulu banokukwazi ukufumana imiphumo emibi ye-SNRIs. Ukuba ungumdala omdala uthatha i-SNRIs, xela ugqirha wakho malunga nemiphumo emibi.
> Imithombo:
> Dell'Osso, B., Buoli, M., Baldwin, DS, & Altamura, A. (2010). > I-Serotonin norepinephrine > i-reuptake inhibitors (i-SNRIs) kwiingxaki zokukhathazeka: ukuhlaziywa okubanzi kokusebenza kwabo kliniki. I-Psychopharmacology yabantu: iCliniki kunye noVavanyo , 25 (1), 17-29.
> Gorman, JM, & Kent, JM (1999). I-SSRIs kunye ne-SNRI: Ibalaseleyo ebunobuninzi ngaphezu kokudakumba okukhulu. Ukuvavanya ukuQinisekisa okuPhezulu: Ukuhlaziywa kwakhona, uJan 1998, iPhoenix, AZ, US . Abagqirha bezithuba zoPhulo lweeKlasi.
> Silverman, uHarold M. (2010). Incwadi yePilisi. 14. ENew York, NY: Iincwadi zeBantam.