Isiza esetyenziselwa ukunceda abantu bayeke ukutshaya sinokubanceda abanxilisayo banciphise inani abayiselayo, ngoko banciphisa izinga labo lokusetyenziswa kotywala. Uphononongo lweyeza lwe-varenicline, oluthengiswa njengeCantix, luncitshise kakhulu izinga lokusetyenziswa ngabasebenzi be - smoking -heavy smokers , ababefuna unyango lokubhema, kungekhona utywala.
Abaphandi bakholelwa ukuba le nkunkuma ingaba yonyango olutsha kulabo bafuna ukunciphisa izinga labo lokusela.
Kwi-Wheeler Centre ye-Neurobiology ye-Addiction kwisikhululo se-Ernest Gallo kunye neCandelo loPhando kwiYunivesithi yaseCalifornia, eSan Francisco, abaphandi bafunda izigulana ezingama-64 zifuna unyango lokuyeka ukutshaya kwixesha eliveki le-16. Icandelo leqela lanikezwa i-Chantix kunye nelinye indawo ye-placebo.
Umyinge weNombolo yeZiselo eziNcitshiswayo
Abathathi-nxaxheba abathatha i-Chantix bancitshiswe inani labo lokusela ngesonto nge-35.32% xa kuthelekiswa nalabo bathatha indawo ye-placebo. Abaphandi bafumanisa ukuba iziphumo zamachiza ekuphuzeni zahluke kwimiphumo yazo ekubhekeni - kwakungabikho ukulungelelaniswa phakathi komyinge wesiselo esisiselo kunye nomyinge we-cigarettes abayibhema.
Uphononongo lufumene ukuba i-Chantix ayizange inciphise inani leentsuku ngeveki abathathi-nxaxheba batywala kodwa bancitshisa inani lezonxila abazidlayo xa baphuza.
"Abantu baqalisa ukusela ngesantya esifanayo, kodwa baphuza ngaphantsi xa beqala," kusho umlobi okhokelayo uJennifer Mitchell. "Ukuba umzekelo wakho oqhelekileyo wawuza ekhaya kwaye ube neebhiya ezimbalwa, uya kwenza njalo, kodwa unokuba enye okanye ezimbini endaweni esikhundleni sezine okanye ezintlanu."
Ukunciphisa ukuNxila okuMngcipheko
Ababhali baphetha ngokuthi i-Chantix inokubaluleka ekunciphiseni ubungozi obubangelwa ukusetyenziswa kakubi kotywala .
"Ukuba okwamanje usela iziselo eziyisixhenxe ebusuku, kwaye sinokuzijika zibe zimbini okanye ezintathu, ngoko awukusela kuphela kwinqanaba elikulimaza ngaphantsi, awunako ukulimaza abanye, ngokunjalo. sinokunciphisa iirhafu zokuqhuba ukushayela, ukutshatyalaliswa komtshato kunye nokusetyenziswa kakubi komntwana kunye neminye imiba yesiqhelo yobunxila, oko kuya kuba yinto enzima, "kusho uMitchell kwingxelo yeendaba.
I-Chantix inceda abantu bayeke ukutshaya ngokuthintela imiphumo emihle ye-nicotin engqondweni. Ababhali bakholelwa ukuba utywala kunye ne-nicotine basebenzisa indlela eqhelekileyo kwingqondo ukuze banike iimvakalelo kunye nomvuzo.
Imiphumo engezantsi kwiqela elilawulwayo
I-Downside i-Chantix, nangona kunjalo, yimiphumo emibi yokuvelisa uxinzelelo kunye neengcinga zokuzibulala. Kulo pho nonongo, abaphandi bathi iziphumo zecala ziphantsi kwaye zancitshiswa ngexesha elide, kodwa oko kungabangelwa kukuba abathathi-nxaxheba bahlolwe ngenyameko ingxaki yempilo yengqondo ngaphambi kokuba bavumeleke kwisifundo. Abaphandi bacebisa iingcamango zexesha elizayo kunye nabathathi-nxaxheba abanesifo sengqondo sezempilo kunye nabaxhasi abakhulu abangabhemi.
Umthombo:
UMitchell JM, et al. "I-Varenicline iyanciphisa ukusetyenziswa kotywala ngokubhema kakhulu." Psychopharmacology . 1 Meyi 2012.