I-Clonidine yinyango eyayibekwe ekuqaleni ukunceda abantu abanegazi eliphezulu. Nangona kunjalo, ngenxa yempembelelo yokuthoba emzimbeni, i-clonidine ifunyenwe ukunceda abantu abaneempawu ze-ADHD ezifana nokunyaniseka, ukunyanzeliswa, ukunyanzeliswa, ukuxhatshazwa, kunye nobunzima bokulala.
Ngo-2010, i-US Food and Drug Administration (i-FDA) yamkelwe i-clonidine njengamachiza kubantwana abane-ADHD ukuba bathatyathwe yedwa okanye ngeyeza ezikhuthazayo.
Amagama okurhweba nge-clonidine afaka uCapapres® kunye neKapvay®.
Sibanzi
I-ADHD imishishini ikwahlula ngokubanzi njengento ekhuthazayo kwaye ingakhuseli. I-Clonidine ithathwa njengonyango olungakhuseliyo lwe-ADHD
Izikhuthazo (ezibizwa nangokuthi i-psychostimulants) ngokuqhelekileyo ngumgca wokuqala wemithi esetyenziswa kwi-ADHD. Umgca wokuqala uthetha ukuba ngokuqhelekileyo zikhetha kuqala unyango. Ziyimichiza ye-ADHD imiselweyo ngenxa yokuba bayayaziwa ukuba iyona ndlela efanelekileyo kakhulu yokunciphisa iimpawu ze-ADHD ezifana nokunyanzelisa, ukunyanzeliswa, nokungaqondakali. Kukho iintlobo ezimbini zokuvuselela: i-amphetamines kunye ne-methylphenidates. Imizekelo yi-Adderall® kunye neRitalin®.
Imithi engeyiyo ivuselela imiselwe ukuba umntu angayinyamezeli unyango olushukumisayo ngenxa yemiphumo emibi. Amachiza angakhuseliyo anokunyulwa ukuba umntu unesizathu sokuthi kungani izikhuthazo zingenakumiselwa, ezifana nezifo ezithile zengqondo, ukuphazamiseka kokulala, izifo zenhliziyo, okanye imbali yokusetyenziswa kakubi kweziyobisi.
I-Strattera® (i-atomoxetine) iyeza elichasayo i-Wellbutrin® XL (i-bupropion hydrochloride) kunye neziyobisi ezichasene ne-Intuniv® (i-Guanfacine) ziyimimiselo yamanye amayeza angakhuselekanga.
Izikhuthazo ezichasene nee-Non-stimulants
Umsebenzi okhuselekileyo we-ADHD unyango ngokubangela ukuba i-dopamine ephezulu kunye ne-norepinephrin ibe khona kwiintetho zesiguphu.
Olu konyuka luvuselela inkqubo yentsholongwane kunye nokuphucula ukusebenza kogcino, njengokufumana ulwazi kunye nokuqonda. Ngenxa yokuba inkqubo ye-nervous is stimulated, abanye abantu bavakalisa i-jittery, bexhala, kwaye baphawule xa bethatha imithi ekhuthazayo.
Clonidine isebenza ngokuhlukileyo. Esikhundleni salokho, kubangela ukuba ubuchopho buyithumele iimpawu kwiimivenge zegazi ezinciphisa uxinzelelo lwegazi. Ukongeza, i-Clonidine ikhupha i-norepinephrin kwindawo ye-prefrontal ye-cortex kwindawo yengqondo. Le yindawo apho imisebenzi yesigqeba yengqondo ikhona, njengokucwangcisa, ukuhlela, nokusebenzisa ulwazi kunye namava. Oku kuvumela umntu ukuba azinzileyo ngokomzimba, kodwa ugxininise ingqondo.
Izinzuzo
Iphucula impembelelo yokukhuthaza
I-Clonidine inokumiselwa ukongezelela kumachiza avuselelayo. Oku kunokuphucula ukuphumelela kokuvuselela.
Ukutya okungahambiyo
I-Clonidine isondlo sithatha inxaxheba, ithetha ukuba ayinyuli okanye isinciphise ukutya. Isifiso sinokuthi sicinezeleke xa umntu ethatha imithi ekhuthazayo, enokuba yinkinga kubantu abangaphantsi.
Kunciphisa ukuxhalabisa
Abantu abane-ADHD bahlala bexhalabisa. Amachiza avela kwintsapho ye-benzodiazepine, njenge-Xanax® okanye i-Valium®, isoloko imiselwe ukuba ixhala.
Nangona kunjalo, ezi zinto zibhekwa njengomkhwa kwaye ziyakuchukumisa kakubi imisebenzi engqondweni. Ngesi sizathu, i-clonidine isoloko imiselwe ukuba kuncede abantu abane-ADHD abanenkxalabo.
Iingxaki zokulala zeengxaki
Ingxaki yokulala enye ingxaki yabantu abaninzi abane-ADHD ubuso. Isiphumo esinokuthi sithathe i-clonidine sinokukunceda ukuphucula ukulala. Enyanisweni, oogqirha banquma umthamo ophantsi we-clonidine 'ngaphandle kwelebula' (oku kuthetha ukusebenzisa isicatshulwa esivumelekileyo se-FDA ukusetyenziswa okungavumelekanga) ukunceda ngokulala.
Nangona i-benzodiazepine yokulala imithi ingagwenywa ngenxa yokuba ingaba ngumkhuba wokwenza, i-clonidine ayithathwa njengokwenza umkhuba.
Uxinzelelo lwegazi ophezulu luyancitshiswa
Ukuba umntu une-ADHD kunye nokunyuswa kwengcinezelo yegazi emva koko i-clonidine inokukhetha okulungileyo. Kuya kunceda ukunciphisa uxinzelelo lwegazi kunye nokunceda ukunyanga iimpawu ze-ADHD.
I-Tourette Syndrome kunye neTic Disorder
Ukuba umntu uneTretret syndrome kunye ne-ADHD, i-clonidine inokunceda iimpawu zombini. Ukudibanisa i-clonidine kunye neyeza ezinomdla kunokunceda kwisifo se-tic.
Imiba
Ayinakunceda Zonke iintetho ze-ADHD
I-Clonidine inceda ukuxhatshazwa, ukunyanzeliswa, ukugonywa, ukuxhamla, kunye nobunzima bokulala. Nangona kunjalo, akufunyanwanga ukuba luncedo kwizibonakaliso ezingapheliyo ze-ADHD.
Uphando oluthile kwi-ADHD yabantu abadala
Izifundo zibonise i-clonidine inokunceda iimpawu ze-ADHD kubantwana nakwishumi elivisayo. Nangona kukho uphando oluncinane lokubonisa ukusebenza kwe-clonidine kwi- ADHD yabantu abadala . Oku kungenxa yokuba iimpawu zokuthi i-clonidine inceda kakhulu, njengobundlobongela, ukunyanzeliswa nokunyanzeliswa, kudla ngokunciphisa.
Ukuphumelela ngaphantsi kunezikhuthazo
I-Clonidine ayisebenzisekanga njengamachiza avuselelayo ekuphatheni iimpawu ze-ADHD. Nangona kunjalo, iziphumo ze-clonidine zibalulekile ngokwaneleyo ukuba i-FDA ivume ukusetyenziswa kwayo kwi-ADHD.
Ingqumbo yeBrain
Esikhundleni sokwandisa amandla okugxila, abanye abantu bafumana i-clonidine inciphisa ugxininiso lwabo okanye kubangela 'inkohlakalo yengqondo.' Iingxaki ezinokukwazi ukugxila ingasesikhashana, njengoko umzimba uphendukela kwi-clonidine. Nangona kunjalo, abanye abantu bafumana le ngxaki iyaqhubeka.
Ndiziva Ndilele
Nangona ulala ebulungeni ebusuku kunokufumana inzuzo efanelekileyo yokuthatha i-clonidine, abanye abantu bazizwa bexinzekile okanye bahlala emini. Oku kunokuba nemiphumo emibi kwisikolo okanye ukusebenza komsebenzi. Ngamanye amaxesha, ukulala kunciphisa ixesha. Oku kuyimpembelelo ebalulekileyo yecala ukuba ugqirha kufuneka ayenziwe, njengoko inokuthi ibe yingozi xa umntu eqhuba isithuthi okanye esebenza ngemishini.
Dysfunction Erectile
Impendulo yamadoda ethatha i-clonidine yi-erectile dysfunction (ED). Nangona umntu enokuziva enentloni ukuthetha nogqirha, ugqirha uya kuqonda ukuba oku kuyimpembelelo yecala eliqhelekileyo kwaye uya kufuna ukukunceda ukulungisa le ngxaki.
IiFom kunye neSistim
Xa i-clonidine ibhalwe kuqala, ngokuqhelekileyo iqondo eliphantsi kakhulu. Oku kungaba ngu-0.05 ukuya kwi-0.1milligram ukuqala. Ukusebenza nogqirha, i-dose yanda ngokunyuka ize ifikelele i-dose esebenzayo. Iipilisi (Catapres®) ziza kwi-0.1, 0.2, ne-0.3 milligram. Ukukhululwa okwandisiweyo (Kapvay®) kufumaneka kwi-0.1 no-0.2 milligram.
I-Clonidine ifumaneka nakwii-patches. Iintlanzi zokugqibela iintsuku ezisixhenxe. Ziyindlela efanelekileyo kumntu ovame ukulibala ukuthatha amayeza okanye engathandi ukugwinya amaphilisi. Emva kokuba i-dose yokwelapha ifunyenwe esebenzisa amacwecwe, ukuba ne-clonidine patch iyona khetho.
Kudala ixesha elivakalelwa ngayo
Kungathatha iiveki ezimbalwa ukuba ubone imiphumo epheleleyo ye-clonidine kwiimpawu ze-ADHD, kodwa enye ingcono ingenzeka ngokukhawuleza.
Imiphumela
Iziphumo eziqhelekileyo zeclonidine ziquka ukukhathala, intloko, isisu, umlomo owomileyo, ukuthukuthela, iintlungu ezisezantsi, iingxaki zokuziphatha kunye nokunyanzeliswa kwegazi. Ezi zinto zihlala zinciphisa emva kwexesha lokuthatha leyeza.
Imiphumo engathí sina kodwa ehamba phambili iquka intliziyo engavumelekiyo, intlawulo yeengqondo ezincitshisiweyo, ukuhlaziya. Umntu ofumana ezi okanye ezinye iziphumo zecala eziqhubekayo kufuneka axhumane nodokotela ngokukhawuleza.
Umntu onomlando wexinzelelo lwegazi ophantsi ngaphambi kokuba athathe i-clonidine inokuba yinto eninzi yokuziva utyhefu, ukunyaniseka kunye nokunyamekela xa uthatha i-clonidine. Abantu abaninzi bayakulibala ukuthabatha amayeza abo-ukuba wenzayo, akufanele kuthatyathwe i dose ephindwe kabini, njengoko loo nto ingakwazi ukunyanzeliswa kwegazi.
Kubalulekile ukuba i-clonidine ingavumi ngokukhawuleza, njengoko oku kungenza i-blood pressure ephezulu ivuseleleke. Kunoko, idosi kufuneka iyancipha kancane kancane. Ugqirha unako ukubonelela ngeengcebiso kwixesha elihle lokupasa.
I-Clonidine yimizi yeCandelo C. Oku kuthetha ukuba ityhuse engasilungele umntwana ongakazalwa. Kubalulekile ukuba umfazi axelele ugqirha wakhe ukuba ukhulelwe, uncelise, okanye uceba ukukhulelwa.
Isishwankathelo
Isishwankathelo, ngelixa i-clonidine ayidla ngokukhetha okokuqala imithi ye-ADHD, kunokunceda ekuphatheni iimpawu ze-ADHD, nokuba yedwa okanye idibene namanye amayeza e-ADHD. Ukuba unomdla kulo njengokhetho lwenyango, yinyusa kunye nodokotela wakho. Baya kunceda ukunquma ukuba kulungile kuwe.