ULobelia ( Lobelia inflata ) sisityalo esisetyenziselwa unyango lwezonyango kunye neyeza lasekhaya. Wathi ukukhupha i-mucus kwindlela yokuphefumula, isoloko isetyenziswa ukuphatha iingxaki zokuphefumula. Ukongeza, abanye abantu basebenzisa lobelia ukuba bancede bayeke ukutshaya .
I-compound efunyenwe kwi-lobelia, i-lobeline yayisisithako esifanayo kwiimveliso ezingaphezulu kwee-counter ukusetyenziswa ekunciphiseni iimpawu ezinxulumene nokukhishwa kwe-nicotine.
Nangona kunjalo, ngowama-1993, i-US Food and Drug Administration yanikezela ukuthengiswa kwemveliso yokuchasa ukubhema ene-lobeline, ngenxa yokungabikho kobungqina bokuba isithako siphumelele njengenxalenye ye-nicotine.
Ukusetyenziswa
Ngenye iyeza, i-lobelia ithathwa njengesiluleko semvelo kule miqathango yempilo elandelayo:
- Isifuba
- Bronchitis
- Isiqhamo
- Ukuxinezeleka
- Pneumonia
Ukongezelela ekuxhaseni ekuncedeni ukuyeka ukutshaya, i-lobelia kuthiwa ixhasa ukubuyiswa kotywala.
Xa isetyenziswe kwisicatshulwa (oko kukuthi, ngokuthe ngqo kwesikhumba), i-lobelia isetyenziselwa ukunciphisa ubuhlungu besisu, ukuphatha izilwanyana zezilwanyana kunye neengqungquthela, nokukhuthaza ukuphulukiswa kwemivimbo kunye ne-sprains.
Izinzuzo
Okwangoku, uphando malunga neenzuzo zezempilo zeLobelia luye lwaveza iziphumo ezidibeneyo. Nanku ukukhangela kwiziphumo ezininzi eziphambili kwimiphumo yempilo ye-lobelia:
1) Ukubhema
Nangona uphando oluthile lwezilwanyana lubonisa ukuba i-lobeline inokunceda ekuphekeni ukuyeka ukutshaya, ingxelo epapashwe kwiDatabase yaseCchrane yeeNkqubo eziPhononongo ngo-2012 yagqiba ukuba akukho bungqina obuvela kwizilingo zexesha elide ezibonisa ukuba i-lobeline inokunceda abantu bayeke ukutshaya.
Ngaphezu koko, uhlalutyo lwengxelo yocwaningo lwexesha elifutshane lucacisa ukuba i-lobelia ibonakala inganikezeli inzuzo njengoncedo lokuyeka ukutshaya.
Kuphando lwezilwanyana (njengoluphando olusekelwe kumatshini olupapashwe kwi- Journal of Pharmacology kunye ne-Experimental Therapeutics ngo-2000), izazinzulu ziye zaphawula ukuba i-lobeline inokuba nomsebenzi onjenge-nicotine kwaye inokunceda ukukhululwa kwe-dopamine (iikhemikhali yengqondo edlala indima ekuveliseni iimvakalelo kunye nenhlalakahle).
2) Utywala
I-Lobeline inokunceda ukuphatha utywala, ngokutsho kwiphando lokuqala elipapashwe kwi- Physiology & Practice in 2009. Kwiimvavanyo kumagundane, abaphandi bafumene ukuba ukuchithwa kwamanzi kwanciphise kakhulu ukunyulwa kwezilwanyana kunye nokunciphisa utywala.
3) Uxinzelelo
Uphando oluphambili lubonisa ukuba i-lobeline ingaba nefuthe elichasayo. Ngophando luka-2013 olupapashwe kwiNkqubo-phambili ye-Neuro-Psychopharmacology kunye ne-Biological Psychiatry , umzekelo, iimvavanyo kwiigundane zibonise ukuba i-lobeline inokunceda ekunciphiseni ukudandatheka ngokuchaphazela ezinye iikhemikhali zeengqondo ezichaphazelekayo ekulawuleni imizwelo.
Imijelo
Nangona inokukhuseleka kwabanye abantu ukuba bathathe i-lobelia kwizilwanyana ezincinane okanye kwizilungiso ze-homeopathic, amanani athatywayo aphakathi kwamanzi angabangela iziphumo ezinjenge-diarrhea, umlomo owomileyo, isisonguluko, intliziyo esheshayo kunye nokuhlanza.
Ekubeni kukho inkxalabo yokuba i-lobelia i-mody-to-large dose idibene nayo inokubangela iziganeko ezibi kakhulu ezinjengezigulane, i-coma, kwaye mhlawumbi nokufa, kungcono ukuphepha i-lobelia ngokupheleleyo (kwaye ukuba usacinga oko, kubalulekile ukubonisana yakho ugqirha ngaphambi kokuba athathe nayiphi na imali).
Kubaluleke kakhulu kubantu ngabanye abaneemeko ezinjengezonyama, isifo senhliziyo, uxinzelelo lwegazi oluphezulu, izifo zengqondo kunye nesifo sesibindi sokuphepha ukusetyenziswa kwe-lobelia.
Ezinye iindlela
Ukuba ufuna isiluleko esingokwemvelo ukukunceda ukuyeka ukutshaya, kukho ubungqina bokuthi isilwanyana saseSt. John singaba luncedo. Ngaphezu koko, uphando oluthile lubonisa ukuba ukwenziwa kwe-acupuncture okanye hypnotherapy kunokunceda ukuyeka ukutshaya.
Ukwenziwa kwe-Acupuncture kunokunceda ukuncedisa ukubuyiswa kotywala. Uphando oluphambili lubonisa ukuba iilube ezinjengobisi obunxantathu kunye neadzu zinganceda ekunyangeni utywala.
Benzisa iLobelia
Ngenxa yokungabikho kokuxhasa uphando kunye nemingcipheko yempilo enzima, i-lobelia ayikwazi ukunconywa. Izibonelelo azange zivavanywe ukhuseleko kwaye ngenxa yokuba izongezo zokutya zikhululekile kakhulu, umxholo weemveliso ezithile zingahluka kwizinto ezichaziweyo kwilebula yomkhiqizo.
Kwakhona ugcine ukhumbule ukuba ukhuseleko lwezongezelelo kwabasetyhini abakhulelweyo, oomama abangabongikazi, abantwana kunye nalabo abanezifo zonyango okanye abo bathabatha imishanguzo ayilwanga. Ukuba ucinga ngokusetyenziswa kwe-lobelia, ncokola nomboneleli wakho oyintloko. Ukuziphathela imeko kunye nokuphepha okanye ukulibazisa ukunakekelwa okuqhelekileyo kunokuba nemiphumo emibi.
Imithombo
Farook JM1, Lewis B, uGaddis JG, uLittleton JM, uBarron S. "I-Lobeline, i-agonist ye-nicotin ekhethekileyo inqanda ukusetyenziswa kotywala kunye nokukhethwa kwintlanzi yeC57BL / 6J. Physiol Behav. 2009 Juni 22; 97 (3-4): 503-6.
McChargue DE1, Collins FL Jr, Cohen LM. "Impembelelo yokutshintshwa kwendawo yokuthunga i-non-nicotinic kunye ne-lobeline kwiimpawu zokuhoxiswa kwi-48-h yokutshaya itekisi engabikho." INicotine Tob Res. NgoMeyi ka-2002; 4 (2): 195-200.
Roni MA1, Rahman S. "Imiphumo efana ne-Antidepressant-like of lobeline kwiigundane: ukuziphatha, i-neurochemical, ne-neuroendocrine ubungqina." Prog Neuropsychopharmacol Biol Psychiatry. 2013 uMatshi 5; 41: 44-51.
Sántha E1, Sperlágh B, Zelles T, Zsilla G, Tóth PT, uLendvai B, uBaranyi M, Vizi ES. "Iinkqubo ezininzi zamaselula zidibanisa umphumo we-lobeline ekukhululweni kwe-norepinephrin." J Pharmacol Exp Ther. 2000 Julayi; 294 (1): 302-7.
I-Stead LF1, uHughes JR. "Lobeline yokuyeka ukutshaya." I-Cochrane Database Syst Rev. 2012 Feb 15; 2: CD000124.
I-Subarnas A1, Oshima Y, Sidik, Ohizumi Y. "Umgaqo wokuxhatshazwa kweLobelia u-L. (Campanulaceae)." J Pharm Sci. 1992 Jul; 81 (7): 620-1.
Subarnas A1, Tadano T, Nakahata N, Arai Y, Kinemuchi H, Oshima Y, Kisara K, Ohizumi Y. "Indlela ekhoyo yokuxhatshazwa kwengqondo ye-beta-amyrin palmitate ehlukeneyo ukusuka eLobelia igqithisa imifuno ekuqhutyweni kobhukuda." Life Sci. 1993; 52 (3): 289-96.
Ukuziphendulela: Ulwazi oluqulethwe kule ndawo lujoliswe kwiinjongo zemfundo kuphela kwaye alithathi indawo yeengcebiso, ukuxilongwa okanye unyango ngumgqirha onelayisenisi. Akunakuthetha ukukhusela zonke iindlela zokulondoloza, ukusebenzisana kwezidakamizwa, iimeko kunye nemiphumo emibi. Kufuneka uncede unyango lwangonyango ngokukhawuleza kuyo nayiphi na imiba yempilo uze ubonane nodokotela wakho ngaphambi kokusebenzisa elinye iyeza okanye wenze utshintsho kwi-regimen yakho.