Isizathu esona sizathu sokuba silale siye sahlala sisinye sezinto ezifihlakeleyo zesayensi yanamhlanje. Iingcamango ezahlukileyo ezininzi ziye zacetyiswa, kodwa inyaniso kukuba akukho mntu uqiniseke ukuba kutheni sichitha malunga nesithathu ebomini bethu belele.
Kukho uphando oluninzi lubonisa indlela ukulala kusiza ukuhlanganiswa kweememori nokulungisa umzimba, kodwa ezininzi iinzululwazi zikholelwa ukuba ezi ntshukumo azichazi ngokupheleleyo injongo yokulala, ngokukodwa kwimibono yokuziphendukela kwemvelo.
Ukuchitha ixesha lobomi bethu obuthongo kunye nabasengozini kuvula ingozi enkulu, ezininzi iingcali zikholelwa ukuba kukho isizathu esibangela ukuba silale .
Uphando olutshanje, nangona kunjalo, lunikeza ngakumbi ukukholelwa kwenye yeengcamango zokulala, okubonisa ukuba ukulala kubalulekile ukuvumela ingqondo ukuba ihlambulule kwaye iqalise kwimisebenzi yosuku lwangaphambili.
Uphando olupapashwe kwiphepha le-2013 le- Sayensi lityhila ukuba ubuthongo lunikeza ingqondo ithuba lokuzihlambulula. Isifundo ngokwayo sichaphazela ukujonga ukuhamba kwamanzi kwiintsholongwane zamagundane ekuvukeni nasekuphumeni. Abaphandi bajolise ngokukodwa malunga nendlela amanzi aphuma ngayo ngaphakathi kwenkqubo ye-glymphatic okanye izikhala phakathi kwe- neurons . Le nto ifana neenkqubo zokulahlwa kwenkunkuma, ukukhupha iimveliso zentengiso ezenziwe ngamaqenjini engqondo xa wenza imisebenzi eqhelekileyo.
Umkhuhlane weFluid ukwanda kwiBongo
Nangona kunjalo, ukuthunyelwa kwezixhobo zokungcola kudinga amandla amaninzi, kwaye abaphandi baxilisa ukuba ingqondo ayinakukwazi ukuxhasa le mi sebenzi yokucoca kunye nenkqubo yolwazi lwenzame ngexesha elinye.
Ukuvavanya le ngcamango, umbhali ohamba phambili, u-Lulu Xie, wachitha iminyaka emibini yokuqeqeshwa iigundane ukuze alele ebomini yombroskopu eya kubavumela abaphandi ukuba bagcine idayi ehamba ngeethambo eziphilayo.
Emva kokuba umsebenzi we-EEG uqinisekisile ukuba iigundane zazilele, udayi obomvu wawufakwe kwi-cerebrospinal fluid yabo.
Isiqingatha seyure kamva iigundane zavuswa kwaye idayi ebomvu yabuya ijojowe. Ngalolu hlobo, abaphandi bakwazi ukubukela ukuhamba komnxeba obomvu nokubomvu ngokusebenzisa ubuchopho. Oko bakubona kukuba ngelixa inani elikhulu le-cerebrospinal fluid liphuma phakathi kwengqondo ngexesha lokulala, ukunyanzeliswa okuncinci kwakuboniswa xa bevukile.
Izikhala phakathi kwamaCells eBrains ziba zikhulu ngexesha lokulala
Ngoko kutheni kubakho ukukhupha okukhulu kwamanzi ngexesha lokulala kunokuchasene nokuvuka? Abaphandi baphinde babone ukuba izikhala zomphakathi phakathi kweeseli zengqondo zaba zikhulu xa zilala, zivumela ukuba amanzi aphumelele ngokukhululeka. Ezi ziteshi zanda malunga nama-60% ngexesha lokulala. Abaphandi bafumene xa iiprotheni ezithile zafakwa kwiigundane, iiprotheni zacinywa ngokukhawuleza ngexesha lokulala.
Impembelelo enokwenzeka
"Ezi ziphumo zinempembelelo ebalulekileyo ekuphatheni izifo 'ezingcolileyo' njengesifo se-Alzheimer," kutsho uMaiken Nedergaard, omnye wabalobi abafundayo. "Ukuqonda ngokucacileyo indlela kwaye xa ubuchopho busebenza njani inkqubo ye-glymphatic kunye nokucima inkunkuma kuyimfuneko yokuqala yokuzama ukulungelelanisa le nkqubo kwaye yenza ukuba isebenze ngokufanelekileyo."
Izazinzulu ziye zaziwa ixesha elide ukuba ezinye iimeko zesifo sengqondo ezinjenge-dementia, i-Alzheimer's ', kunye nesifo sohlangothi ziyahlanganiswa nokuphazamiseka kokulala. Ngokutsho kweNedergaard, ezi ziphumo zingase zibonise ukuba ukungabikho kokulala kungadlala indima ebalulekileyo kwiimeko ezinjalo. Ngoku ukuba abaphandi baye bafumanisa le nkqubo yokucoca ingqondo, ithemba labo kukuba kuya kubangela uphando olongezelelweyo malunga nendlela le nkqubo isebenza ngayo kunye nenxaxheba enokuthi idlale kwiimeko zeengxaki ezifana ne-Alzheimer's disease.
Uphando luphinde luphinde lubonise ukubaluleka kokulala. "Oku kunokuvula iingxoxo ezininzi kubaqeshwa be-shift, abasebenza ngexesha lobusuku," uNedergaard watshela iSayensi .
"Mhlawumbi ube nomonakalo ukuba awufumani ukulala kwakho."
> Imithombo:
> Underwood, E. (2013, Oktobha 17). Ukulala: Ingqondo ephezulu? Sayensi .
> Xie, L., Kang, H., Xu, Q., Chen, MJ, Liao, Y., Thyagarajan, M., O'Donnell, J. Nedergaard, M. (2013). Ukulala kuqhuba ukukhutshwa kwe-metabolite kwi-brain brain. Sayensi. 342 (6156), 373-377. INGXELO: 10.1126 / isayensi.1241224.