Iimiphumo zeMpawu zoPhulo kunye nokuKhuselwa kweMpawu zokuLawula
U-Buprenorphine useklasini yemithi ebizwa ngokuthi i-opioid ekhethekileyo ye-agonist-antagonists. Isetyenziselwa kwiipatches ezitshintshileyo kunye namafilimu e-buccal kubantu abafuna imithi ejikelezayo-yeeyure ngenxa yeentlungu ezingenakuphathwa ngamanye amayeza. Isetyenziswe ukukhusela iimpawu zokurhoxisa izigulana eziyeka ukuthatha iziyobisi ze-opioid ngokuvelisa iziphumo ezifanayo kwezi zi yobisi.
I-Buprenorphine yaziwa nangokuthi yi-Suboxone (buprenorphine kunye ne-naloxone), i-Subutex, i-Belbuca, iBuprenex, i-Butrans, i-Temgesic, ne-Bupe
Ukufunda indlela ezenza ngayo kwinkqubo yakho kwaye ziphi ukusebenzisana ezinokusetyenziswa kunye nezinye iziyobisi kunokukunceda uqonde iindlela zokukhusela kunye nendlela yokukhusela ukugqithisa.
Buprenorphine kwiNkqubo Yakho
I-Buprenorphine i-opioid enamandla, ehlala ihlala njalo kwaye nokuba uyayithatha ngokwemiyalelo yakho ugqirha, kufuneka uhlolwe ngenxa yendlela enokwenzeka ngayo, ngakumbi xa uqala ukuthatha i-buprenorphine okanye xa i-dosage ishintshiwe.
I-website ye-FDA iqulethe izikhokelo zeMithi yamagama amaninzi eemveliso ze-buprenorphine. Kufuneka uqhagamshelane nogqirha wakho okanye ezi zikhokelo malunga nokuqapha, izithintelo kunye nolwazi olungakumbi malunga nemveliso nganye.
Imiphumo ye-buprenorphine i-receptors yeentlungu ze-opioid ebuchosheni kunye nentambo yomthambo. Kodwa kuphazamisa amaziko okuphefumula kwengqondo.
Ivelisa abafundi beenkcukacha. Iyanciphisa ukukhwabanisa kwamathambo, oku kunokukhokelela ekubanjeni. Kwakhona i-vasodilator kwaye ke inokuvelisa isikhumba esikhanyayo, ukujuluka, nokuziva utyhafile xa uvuka emva kokulala okanye ukuhlala.
I-Buprenorphine ine- half half-life of 24 to 42 hours. Iphulwe phantsi kwesibindi kwaye ikhutshwe kwi-bile kunye neentso kwi-urine kunye nemifesi.
Ukuhlanganiswa kwemveliso ye-Suboxone, i-naloxone inexesha elifutshane lokuphelisa ixesha kunye nokuphelisa ubuncinane beeyure ukusuka kwiiyure eziyi-2 ukuya kwi-12.
Kukho ukusebenzisana kwezidakamizwa kunye ne-buprenorphine engakhokelela ekuphenduleni okunzima kwaye mhlawumbi okubulalayo. Musa ukusela utywala okanye uthathe nayiphina imithi equka utywala obumhlophe ukuthatha i-buprenorphine. Musa ukuthatha naziphi na izidakamizwa zesitalato.
Ngexa ufanele uxoxe ngawo onke amayeza, i-supplements, iivithamini, kunye nezidakamizwa ezingaphezulu kwezilwanyana kunye noogqirha bakho, ezi ziyizona nkxalabo eziqinileyo: ii-benzodiazepines (njenge-Xanax, iLibrium, iKlonopin, i-Valium, i-Diastat, i-Ativan, i-Restoril, Halcion kunye nabanye), izihlunu ze-muscle, i-sedatives, iipilisi zokulala, izilwanyana ezinxilisayo, amayeza enhlungu, kunye nemichiza yokugula ngengqondo kunye neentlanzi.
Ukuba unqamle ukusebenzisa i-buprenorphine ngokukhawuleza, unokufumana iimpawu zokurhoxisa.
Ukukhusela i-Buprenorphine Overdose
Izibonakaliso ze-buprenorphine overdose zingaquka:
- Phakamisa abafundi
- Ukulala kakhulu
- Utywala
- Umbono ongezantsi
- Ukuphefumula
Ukuba uyakrokrela ukuba umntu uphelile kwi-buprenorphine, biza isikhulu solawulo lweetyhefu kwi-1-800-222-1222. Ukuba ixhoba lehlile okanye lingaphefumli, diza 9-1-1.
Kude kangakanani iBuprenorphine ihlala kwiNkqubo
Ukuzama ukuqikelela ukuba i-buprenorphine ibonakala ixesha elingakanani emzimbeni kuxhomekeke kwimimandla emininzi, kubandakanywa nayiphi na uhlobo lokuqulunqwa kwesilwanyana, nokuba luhlangene nezinye iziyobisi, kunye nemetabolism.
I-Buprenorphine ine-metabolite (i-norbuprenorphine) eyahlukileyo kune-opioid esetyenziswa kakubi kwaye ayikwazi ukuvavanywa kwisicatshulwa seziyobisi ezifana nomsebenzi. Nangona kunjalo, uvavanyo luye lwaba luqhelekileyo. Ukuba unikwe i-buprenorphine okanye umdibaniso we-Suboxone, kufuneka uyixelele kwi-laboratory yokuvavanya ukuze iziphumo zakho ziguqulelwe ngokufanelekileyo. Inokuthi ibonakale kumchamo ngeentsuku ezingama-6, kodwa nangaphezulu ngokuxhomekeke kumetabolism ngamnye. Ingabonwa kwi-screen opioid yomchamo okanye umboniso othile we-urprenorphine.
> Imithombo:
> I-Buprenorphine Information Information. IRobwoodwood Toxicology Laboratory. https://www.redwoodtoxicology.com/resources/drug_info/buprenorphine.
> Buprenorphine Buccal (ubuhlungu obungapheliyo). I-Medline Plus NIH. https://medlineplus.gov/druginfo/meds/a616019.html.
> IBuprenorphine ngeelwimi kunye neBaccal (ukuxhomekeka kwe-opioid). I-Medline Plus NIH. https://medlineplus.gov/druginfo/meds/a605002.html.
> Buprenorphine Transdermal Patch. I-Medline Plus NIH. https://medlineplus.gov/druginfo/meds/a613042.html.