Indlela yokuSebenzisa iSerotonin Reuptake Inhibitors (SSRIs)
I-Reuptake yinto ebalulekileyo yeyeza ukuqonda ukuba unengxaki yomntu ongenamkhawulo (BPD) okanye nayiphi enye ingxaki yempilo yengqondo. Ngoba? Ngenxa yokuba amaninzi amachiza asetyenziswa ukunyanga izifo zempilo yengqondo asebenza ngokutshintshisa inani elithile le-neurotransmitters ethile kwingqondo. I-Reuptake yinxalenye ebalulekileyo yale nkqubo.
Ama-neurotransmitters abathunywa bezakhemikhali ababonelela indlela yokuhambisa iimpawu ezikhishwe ngamaseli enyiti (i-neurons) kuzo zonke i-synaps es (iindawo phakathi kweeseli) ukusuka kwelinye selensi yesinye ukuya kwelinye.
I-Reuptake yinto eyenzeka emva kokuba isignali idluliselwa: I-neurotransmitter, "umsebenzi" wayo ugqityiwe, ubuyisela kwakhona kwisisele esasikhululwe ngaphambili.
Kutheni i-Reuptake ibalulekile kwiNyango yokuCalulelwa kweBPD?
Ukuxinezeleka kwi-BPD kunye nezinye iingxaki zempilo yengqondo zidibaniswa namazinga aphantsi kwamachiza eengqondo, kuquka i-serotonin, i-dopamine kunye ne-norepinephrin.
Ukuba unayo i-BPD kwaye uthabatha amayeza ukunyanga uxinzelelo (ngamanye amagama, unxinzelelo), unokuthi uthathe i -serotonin reuptake inhibitor okanye i-SSRI. I-anti-depressants echazwe ngokuqhelekileyo, i-SSRI isoloko isetyenziselwa ukuphatha abantu abane-BPD ngokunciphisa iimpawu zokulinganisela ukuxinezeleka okukhulu.
I-SSRI yandisa inani le-neurotransmitter serotonin ebuchosheni ngoku, njengokuba uyazi ngoku, unciphisa ukuphindaphinda kwakhona kwiiseli ezidlulisele kuyo. Ngenxa yoko, amazinga aphezulu kunama-serotonin ashiywe ukujikeleza kwingqondo.
Ukwandisa inani le-serotonin ebuchosheni kubonakala kunceda iisilini zeseli zithetha, nto leyo inceda ukuphakamisa uxinzelelo nokuphucula isimo sengqondo. I-Serotonin ibizwa ngokuba yendalo yemvelo "yinto enyanisekileyo" kuba ivelisa umgangatho wokuphila kakuhle.
Njengoko ubona, i-SSRIs ayincedi umzimba ukuba ukhiqize i-serotonin engaphezulu.
Kunoko, banceda umzimba ujikeleze ngaphezulu kwe-serotonin.
Imizekelo ye-SSRIs
Nazi amagama ama- SSRI atholakalayo ugqirha wakho ukuba anikezele:
- Citalopram (Celexa)
- Escitalopram (Lexapro)
- I-Fluoxetine (iPzac, uSarafem)
- Fluvoxamine (Luvox)
- I-Paroxetine (Paxil, Paxil XR, Pexeva)
- Sertraline (Zoloft)
ILizwi Lokulumkisa ngeSerotonin Syndrome
Inkqubo yokuphinda i-reuptake nayo idlala indima kule meko engabonakaliyo kodwa eyingozi, eyenzekayo xa umntu ethatha amayeza emibini enyusa izinga le-serotonin emzimbeni. Oku kungakhokelela kumanqanaba aphezulu ase-serotonin ebuchosheni.
Amachiza ongafanele uwathathe kunye nawo afaka:
- Abaxinzelelo, kuquka ii-SSRI
- Ezinye iintlungu okanye unyango lweentloko
- Imfuyo yongeza intambo yaseSt. John
Izimpawu neempawu ze- serotonin syndrome ziquka:
- Iqondo lentliziyo ekhawulezayo
- Ukuxhalabisa
- Ukutshitshiswa
- Ukungabikho koqhagamshelwano
- Ukudideka
- Ukuxela
- Ukugubha
- Ukungabi naso
Ukuba unayo nayiphi na impawu okanye iimpawu, fumana unyango ngokukhawuleza.
I-serotonin syndrome iyakwenzeka xa uqale uthabathe imithi okanye ukunyusa umthamo.
I-serotonin syndrome ayinqabile, ngokuyininzi ngenxa yokuba oogqirha banonophelo ngokumisela imichiza engayibangela. Nangona kunjalo, ngenxa yokuba le syndrome inobungozi, i-FDA icele abaenzi balezi zidiza zamachiza ukuba babeke iilebhile ezilumkiso kuzo ezinokukuphawula kule mngcipheko.
Imithombo:
"I-SSRIs Isebenza njani." I-Healthline.com (2013).
"Ukudandatheka (ingxaki enkulu yokudakumba): i-serotonin sele ikhethayo inhibitors (SSRIs)." I-Clinical Mayo (2013).
"I-Serotonin Syndrome. MedlinePlus (2016).