Impembelelo kaMolly kwiBrain Inokuhlala Yigcina
Izidakamizwa ezininzi ezingekho mthethweni zenza umphumo kwingqondo. Ngokuqhelekileyo, yikho kutheni abantu basebenzisa iziyobisi kuqala, kuba benza into engqondweni ukuba bazuze phezulu, bavuselele imvakalelo yabo, okanye badale i-hallucinations.
Ngelishwa kumsebenzisi, ezininzi iziyobisi azichaphazeli kuphela imimandla yengqondo eyenza bazive behluke, zinokuchaphazela ezinye iinjongo zobomi obubalulekileyo ekusebenzeni, ukufunda, okanye ukukhumbula.
I-MDMA, eyaziwa ngokugqithiseleyo njengokwenkcenkcesha okanye i-Molly, ayikho enye into. Isebenza kuma-neurotransmitters engqondweni ukuze banike abasebenzisi ukuguqulwa okukhulu kwemoya yabo, kodwa ingabangela ukuba iziphoso zengqondo kunye nokulahlekelwa kwemisebenzi.
I-Serotonin, iDopamine, neNorepinephrin
Xa umntu ethatha i-MDMA, kubangela ukuba i-serotonin, i-dopamine, ne-norepinephrine zikhutshwe kwiindawo zabo zokugcina i-neuron. Oku kubangela ukwanda komsebenzi we-neurotransmitter kwingqondo.
Ukukhululwa kweemali ezigqithisileyo zala ma-neurotransmitter ngokusebenzisa ukusetyenziswa kwezidakamizwa kunokubangela ukuba ingqondo iphelelwe yilezi zithunywa zeekhemikhali nemiphumo emibi.
I-Serotonin, i-dopamine, ne-norepinephrine inxibelelana ngolwazi kuwo wonke ubuchopho. Bahambisa imiqondiso phakathi kweeseli zesisindo.
I-Serotonin inceda ukugcina isimo esifanelekileyo kunye neminye imisebenzi yeemvakalelo kunye nayo ibandakanyeka ekulawuleni imizila yokulala, ukulawula ubuhlungu, kunye nokutya, phakathi kwabanye.
Dopamine yi I-transmitter ibandakanyeka ngokulawula imizwelo kunye nokujoliswa kweminye kunye neminye imisebenzi ye-nervous system.
I-Norepinephrine ingumzabalazo ochaphazelekayo kwimpendulo "yokulwa kunye neendiza" kunye nokulawulwa kwemizwelo, ukuxhalaba, ukulala, amandla nokugxila.
Kuye kunzima izazinzulu ukuba zifunde iziphumo ze-MDMA ekusebenziseni ingqondo yengqondo kuba ubugcisa bokubaluleka okufunekayo ukwenza njalo abukho.
Ngoko ke, ininzi yophando malunga nendlela i-MDMA echaphazela ngayo ubuchopho sele yenziwe ngezilwanyana zebhoratri.
Nangona kunjalo, uphando oluye lwafunyanwa lufumene ukuba i-MDMA ivelisa ukukhululwa okukhulu kwe-serotonin kunye nokukhululwa kwe-dopamine engaphantsi kwamanye ama-stimulants afana ne-methamphetamine.
Abaphandi bakholelwa ukuba kukukhululwa kweemali ezininzi ze-serotonin ezivelisa iziphumo eziphakamisa iziphumo zabasebenzisi be-MDMA.
Kodwa, i-serotonin inendima ebalulekileyo ekulawuleni ubuthongo, intlungu, imvakalelo, ukutya kunye neminye imisebenzi. Xa i-MDMA ibangela ukukhululwa kwemali eninzi ye-serotonin, ingqondo ingakwazi ukupheliswa kwayo kwaye igalele kwimiphumo embi emva kokubangela ukuba abasebenzisi abaninzi bahlaselwe emva kokuthatha i-MDMA .
Iimiphumo ezihlala ixesha elide kwiBongo
Uphando lwezilwanyana lubonise ukuba umonakalo owenziwe yi-MDMA kubangela ukuba i-neurons ene-serotonin inokuhlala ixesha elide. Ukulinganisa ukusetyenziswa kwexesha elide lokusetyenziswa kwe-MDMA kubantu kubonakaliswe nzima kunosayensi, kodwa ezinye izifundo ziye zafumanisa ukuba abanye abasebenzisi abanezakhono ze-MDMA:
- Udideko oluhlala ixesha elide
- Ukuxinezeleka
- Ukukhunjulwa kwememori
- Ukunyamekela iinkqubo
Utshintsho kwiBrain Activity
Ezinye izifundo zokucinga ngomntu zabasebenzisi baseMolly zifumene ukuba utshintsho lweziyobisi kwimimandla yengqondo echaphazelekayo:
- Cognition
- Umoya
- Umsebenzi weMoto
Iimiphumo zezinye iziyobisi
Olunye ucelomngcipheko luye lwaba nokuphonononga imiphumo yokusetyenziswa kwe-MDMA kwingqondo kukuba amaxesha amaninzi amathebhulethi e-ecstasy athengiweyo kwisitrato ayilunganga i-MDMA, kodwa iqulethe ezinye iziyobisi okanye izinto.
Kukho amathuba okuba abasebenzisi be-ecstasy basebenzisa ezinye iziyobisi ezinjenge-marijuana okanye utywala, ezichaphazelayo ingqondo. Ngako oko, kunzima kubaphandi ukuba bafumane ukuba iimiphumo abazijongayo zivela kwi-MDMA kuphela, ezinye iziyobisi, okanye ukudibanisa ezimbini.
Ezinye izinto ezingadlala indima
Ngokubambisana nokusetyenziswa kwamanye amayeza, ezinye izinto ezinokudlala indima kwezinye iingxaki ezingenakucatshulwa eziboniswe kubasebenzisi be-MDMA ziquka:
- Ngesini
- Isistim
- Ukuphindaphinda kokusetyenziswa
- Ubudala bokusetyenziswa kuqala
- Izifo ze-Genetic kunye nemeko yendalo
Ezinye iziphumo ze-MDMA kwiBrain
Kukho uphando lwabasebenzisi bexesha elide be-MDMA abaye babonisa ezinye iziphumo zokusetyenziswa kakubi kweziyobisi:
UkuFomelwa kweFom yehlabathi : Uphando oluthile lufumene ukuba ukusetyenziswa kwe-MDMA ukuzonwabisa kwathintela amandla abasebenzisi bokudibanisa ulwazi lweenkcukacha zoqhelwano lwendawo kwifomu yehlabathi.
Ukuxhamla ngokwesondo : Ngenxa yokuba i-MDMA ithintela amanqanaba e-serotonin ngaphezu kwamanqanaba e-dopamine kwabanye abasebenzisi, abanye abaphandi bakholelwa ukuba ixesha elide lokusetyenziswa lunokubangela ukuphazamiseka kwezesondo kunye nokuqonda kwengcamango yokuthandana.
Ulawulo olungaphelelekanga : Abanye abaphandi bakholelwa ukuba, njengamanye amaninzi amachiza, i-MDMA ithintela ummandla wengqondo echaphazelekayo ngokulawula umgudu kwaye ngenxa yoko unokufaka isandla ekuphuhlisweni kweengxaki zokusetyenziswa kweziyobisi.
Iimpembelelo ezinganeni ezingakazalwa
Kukho uphando olubonisa ukuba ukusetyenziswa kwe-MDMA akuchaphazeli kuphela ubuchopho babasebenzisi kodwa ubuchopho bezingane ezingakazalwa zabasebenzisi abakhulelweyo beziyobisi.
Izifundo zezilwanyana ziye zafumana imiphumo ebalulekileyo ekufundeni nasekukhunjweni xa zibonakaliswe kwi-MDMA ngexesha lokuphuhliswa elilinganayo neyesithathu kwi-trimester ebantwini.
Abaphandi banenkxalabo malunga nemiphumo emibi ye-MDMA ekuphuhliseni abantwana abangazalwa bengabantwana xa abasebenzisi besetyhini abakhulelweyo beqhubeka beyisebenzisa ngenxa yokuphosakela ukuba uMolly "isichengile".
Ngaba ucinga ukuba ungadinga unyango lweziyobisi? Thatha i- Quiz Treatment Screening Quiz ukuze ufumane.
Imithombo:
Isizwe seSizwe sokuLawulwa kweziyobisi. "MDMA (Ecstasy) Ukusetyenziswa kakubi: Yintoni eyenziwa yi-MDMA kwingqondo?" Imibiko yophando ngoMatshi 2006
Schmid, Y et al. "Iimpembelelo ze-methylphenidate kunye ne-MDMA ekuhloliseni i-stimuli kunye nezobudlelwane obusondeleyo." I-European Neuropsychopharmacology ngoJanuwari 2015
Schenk, S et al. "Umrhumo woMngcipheko kunye neReveronin Receptor Neuroadaptations kuPhuhliso lwe-MDMA ('Ecstasy'). Iimxholo ezikhoyo kwiingxaki zeNewscience zeBhodi zikaDisemba 2015
White, C et al. "Iimpembelelo zokusetyenziswa kwe-MDMA 'ukuhlaziya' kwindlela yokucwangcisa ifom yehlabathi." Umbhalo we-Psychopharmacology ngoNovemba 2014